The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But where does translation take place within a cell?

Northwestern Medicine scientists have uncovered new details explaining how poxviruses manipulate host cells to enhance their ...

In this review of RNA therapies, we paint an overview of what’s going on in a field that is addressing a number of diseases.

What instructions prevent premature mRNA translation before fertilization? In the 1960s and 1970s, scientists asked this question and came up with two possible answers. In 1966, Alexander Spirin ...

Harness Therapeutics Ltd. has raised fresh financing to further develop its technology for upregulating the translation of ...

However, the therapeutic effectiveness is limited by the poor translation uptake of naked mRNA. To circumvent this challenge, researchers from VIB, VUB, Ghent University, and eTheRNA ...

You will be redirected to our submission process. RNA-binding proteins, and their interaction with messenger RNA (mRNA), play an important role in the regulation of translation and mRNA decay. The ...

Regulation of the poly(A) tail is essential for selective protein translation in early embryos. However, the mechanisms that determine and maintain the length of maternal mRNA poly(A) tails remain ...

Coller’s lab was the first to show that codons can be a major determinant of mRNA decay in yeast; this work, he says, is the first to show additional layers of complexity in humans. Researchers had ...

mRNA vaccines have the advantages of low production cost, no metabolism and toxicity, and easy modification, but they also have limitations, such as translation instability. Studies have shown that ...

Researchers mapped HIV-1’s translation strategy, revealing RNA elements like uORFs, iORFs and an intricate frameshift site ...

We demonstrate that DDX5 regulates STAT1 mRNA translation by resolving a G-quadruplex (rG4) RNA structure, proximal to the 5′ end of STAT1 5′UTR. We employed luciferase reporter assays comparing wild ...