A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...

Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger ...

RNA splicing is a post-transcriptional modification process that occurs in eukaryotic cells. When a gene is transcribed, the initial RNA product is called pre-mRNA, which contains both coding regions ...

RNA splicing, a process discovered in the late 1970s, allows cells to precisely control the content of the mRNA transcripts that carry the instructions for building proteins.

Alternative splicing enables a single gene to encode multiple mRNA variants and, consequently, diversifies protein isoform products. The advent of deep sequencing technologies has revealed that 95 ...

In a recent article, he showed that when genes are preferentially positioned near speckles, mRNA splicing is significantly more efficient. 4 “It’s huge for the RNA processing field, because now it ...

My lab studies mRNA splicing mechanisms, its dysregulation in cancer and genetic diseases, and the development of RNA-targeted therapeutics.

Large gene reconstitution with mRNA trans-splicing. Lisa Maria Riemayer, PhD, and colleagues from Elvir Becirovic’s lab made REVeRT, a dual AAV vector technology that is flexible and effective.

RNA splicing, a process discovered in the late 1970s, allows cells to precisely control the content of the mRNA transcripts that carry the instructions for building proteins.