RNA splicing requires specific sequences in the pre-mRNA that mark where introns and exons are located. Occasionally, mutations in these sequences can lead to the production of mRNAs that are out ...

Two molecular control factors play a decisive role in what is known as splicing, the cutting and assembly of mature messenger ...

NEW YORK, July 7, 2025 /PRNewswire/ -- According to a new comprehensive report from The Insight Partners, the global mRNA ...

RNA splicing, a process discovered in the late 1970s, allows cells to precisely control the content of the mRNA transcripts that carry the instructions for building proteins.

Alternative splicing enables a single gene to encode multiple mRNA variants and, consequently, diversifies protein isoform products. The advent of deep sequencing technologies has revealed that 95 ...

My lab studies mRNA splicing mechanisms, its dysregulation in cancer and genetic diseases, and the development of RNA-targeted therapeutics.

Serving as a spatial barrier, it allows mRNA splicing to finish up in the nucleus before the intron-free mRNA is translated in the cell’s internal fluid, the cytosol.

In a recent article, he showed that when genes are preferentially positioned near speckles, mRNA splicing is significantly more efficient. 4 “It’s huge for the RNA processing field, because now it ...

Large gene reconstitution with mRNA trans-splicing. Lisa Maria Riemayer, PhD, and colleagues from Elvir Becirovic’s lab made REVeRT, a dual AAV vector technology that is flexible and effective.

RNA splicing is a post-transcriptional modification process that occurs in eukaryotic cells. When a gene is transcribed, the initial RNA product is called pre-mRNA, which contains both coding regions ...

RNA splicing, a process discovered in the late 1970s, allows cells to precisely control the content of the mRNA transcripts ...

RNA splicing, a process discovered in the late 1970s, allows cells to precisely control the content of the mRNA transcripts that carry the instructions for building proteins.