Complex DNA-breakage events such as chromosomal shattering ... such as epidermal growth factor receptor (EGFR) and fibroblast growth factor receptor 1 (FGFR1), are validated drug targets for ...

In this phase I trial, Lai and colleagues evaluated the safety and toxicity of EGFR antisense DNA therapy in 20 patients with advanced squamous-cell carcinoma of the head and neck. All patients ...

Improve workflow and productivity — when patients arrive for imaging sessions without a current creatinine/eGFR workup, the StatSensor Creatinine POC testing can avoid workflow interruptions and ...

Some non-small-cell lung cancers (NSCLC) have changes in a gene called EGFR. If your NSCLC has these mutations, your doctor likely will recommend treatment with targeted therapies that block EGFR.

One of the biggest groups of EGFR-implicated cancers are squamous cell ... contain cell parts such as DNA, RNA, lipids, and proteins. They are secreted into circulation and affect the function ...

Although our blood contains a huge amount of information, technology seems to be still catching up to what we can learn from ...

Alphamab Oncology (stock code: 9966.HK) announced that the preclinical data on two novel bispecific antibody-drug conjugates (ADCs) JSKN021 and JSKN022 were presented as posters at the 2025 American ...

Magnification ×400. (C) Chromatogram of the EGFR DNA sequencing, showing missense mutations L858R (CTG→CGG, heterozygous) in exon 21 and E884K (GAA→AAA, heterozygous) in exon 22 seen in the ...

Objective Many societies recommend using estimated glomerular filtration rate (eGFR) rather than serum creatinine (sCr) to determine metformin eligibility. We examined the potential impact of ...

During a live event, Xiuning Le, MD, PhD, discussed updated intracranial efficacy, overall survival, and safety of ...