In RPA, this recombinase protein binds to primers designed by scientists, then scans the DNA, and inserts the primers into complementary sites in the DNA. Then single-stranded binding proteins called ...

and it therefore can inhibit recombination by blocking Rad51's access to the single strand needed for invasion. In yeast, however, binding of Rad51 to ssDNA is enhanced by the proteins Rad52 and ...

Focusing on the schematic illustration in a, two DNA polymerase molecules are active at the fork at any one time. One moves continuously to produce the new daughter DNA molecule on the leading ...

In 2021, research led by Ryan Flynn, MD, Ph.D., and his mentor, Nobel laureate Carolyn Bertozzi, Ph.D., opened a new chapter ...

In a hair follicle cell, a protein called keratin is made. Lots of it. Many ribosomes can be working on a single strand of mRNA at once. Protein synthesis isn't a slow process, either. A protein ...

Researchers show that glycoRNAs, uncovered by the lab of Nobel Laureate, Carolyn Bertozzi, can be used to fight cancer.

Heme is involved in many metabolic reactions that occur in the body and is sequestered by specific heme-binding proteins such as hemoglobin. A short piece of single-stranded RNA about 21 to 23 bases ...

Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding ... Non-Watson-Crick base pairs can play important roles in RNA secondary structure, protein-nucleic acid ...

An INRS team discovers a new family of enzymes capable of inducing targeted cuts in single-stranded DNA . A few years ago, the advent of technology known as CRISPR was a major breakthrough in the ...

These compounds consist of a piece of single-stranded DNA with a base sequence ... while HDOs bind electrostatically to serum proteins with low binding affinity and are taken up by cells, Chol ...