Electron micrographs of the lumbar spinal cord showed remyelination in EAE-induced, Lingo1-knockout mice, but demyelination in wild-type control mice. Next, the authors tested whether inhibition ...

Although remyelination occurs in many MS lesions ... the repair process and improved brain function related to vision in mice ...

Oligodendrocyte progenitors are very important in human diseases as they are can elicit a repair process known as remyelination which replaces ... of cell and tissue cultures and brains of mice ...

Opportunities that have been identified in this arena include strategies to limit demyelination through oligodendrocyte protection as well as those to promote repair through remyelination.

Our research focuses on the understanding of myelin regeneration (remyelination) and its failure during multiple sclerosis (MS). We aim to reveal how oligodendrocyte progenitor cell function is ...