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References used to create this graphic: Boo, Sung Ho, and Yoon Ki Kim. “The Emerging Role of RNA Modifications in the Regulation of mRNA Stability.” Exp. Mol. Med. (2020). DOI: 10.1038/s12276 ...
Endogenous ADARs edit genetic material in the cell by attaching to naturally occurring double-stranded RNAs and switching out A bases with I bases (left panel in the below graphic). Therapeutic RNA ...
A simple RNA molecule such as this may have been responsible for the evolution of complex life as we know it. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases ...
In the graphics that follow ... inside a fatty membrane that protects a twisting strand of RNA--a molecule that holds the virus's genetic code. Proteins called "S" form spikes that extend from ...
From mRNA vaccines to RNA interference (RNAi) and beyond, discover how RNA therapeutics are reshaping the landscape of genetic medicine. Information you provide will be shared with the sponsors for ...
Sometimes, analyzing our DNA sequences isn’t quite enough. RNA-seq is a next-generation sequencing (NGS)-based technique that looks at the RNA transcripts produced from our DNA, allowing us to look ...
The central dogma of molecular biology suggests that the primary role of RNA is to convert the information stored in DNA into proteins. In reality, there is much more to the RNA story. However ...
Despite that, the first RNA-targeting therapeutic in the market was launched only five years ago, and the vast majority of all Food and Drug Administration–approved drugs target proteins.
Geneticists have for the first time isolated and decoded RNA molecules from a creature that died out long ago. The genetic material — which came from a 130-year-old Tasmanian tiger, or thylacine ...
Dr. Cech is a biochemist and the author of the forthcoming book “The Catalyst: RNA and the Quest to Unlock Life’s Deepest Secrets,” from which this essay is adapted. From E=mc² to splitting ...