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Perspectives: The Year in Quotes—And Cartoons. Published Dec 19, 2008 at 7:00 PM EST Updated Mar 13, 2010 at 7:13 PM EST. By Newsweek Staff . Newsweek Is A Trust Project Member. FOLLOW.

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Be it the original run or the 2016 reboot, the best Powerpuff Girls quotes always manage to remind viewers that, no matter what, girls always rule.