Like Viagra, Stendra, and Levitra, Cialis (the brand name of the active ingredient tadalafil) is highly effective as a ...

Phosphodiesterase 5 (PDE5) inhibitors (eg, sildenafil, tadalafil) do not appear to reduce the risk of Alzheimer disease and related dementias, according to a National Institutes of Health (NIH) study.

There is a class of drugs called “Phosphodiesterase-5 inhibitors” (PDE5 inhibitors.) Such drugs in this class are known as sildenafil, vardenafil, tadalafil, and avanafil.1 These drugs all work by ...

Avanafil is a newer-generation PDE5 inhibitor that’s more selective than older ED pills about how it inhibits enzymes. It’s less likely to cause side effects than older medications and begins ...

In the ‘80s, researchers set out to test a medication called sildenafil citrate for treating high blood pressure and angina ...

The introduction of PDE5 inhibitors as safe and well-tolerated orally active drugs for the treatment of erectile dysfunction has not only become a clinical and pharmaceutical success, but has also ...

Another direction for future research in this space would be to see if PDE5 inhibitors have the same effect on women as on men. “We know that these drugs are being used, of course, for pulmonary ...

Using Medicare fee-for-service claims data from 2007 through 2018, DREAM study researchers matched 2,888 patients with PAH on PDE5 inhibitors (73.6% sildenafil, 26.4% tadalafil) with 2,888 ...

Phosphodiesterase Type 5 Inhibitor Use Following Radical Prostatectomy is not Associated with an Increased Risk of Biochemical Recurrence. Ann Surg Oncol. 2016;23(5):1760-1767. Chung JW, Kim JW, Ha YS ...

Additionally, the PDE5 inhibitors appear to help reverse a patient’s resistance to chemotherapy, and because Viagra is a PDE5 inhibitor, it also becomes an unexpected anti-cancer drug ...

“We did not have data on the use of PDE-5 inhibitors in women in our study, so we do not know if there is a cardioprotective effect similar to the one we saw in men with ED,” Dr. Kloner told MNT.