Research my team and I published in the journal Science Advances in March suggests that long-term exposure to extreme heat ...

DNA methylation and histone modification are important for regulating gene expression and chromatin structure. New evidence suggests there are multiple levels of crosstalk between these marks.

What if extreme heat not only leaves you feeling exhausted but actually makes you age faster? Scientists already know that ...

As interest in DNA methylation continues to grow across both basic and translational research, there is a pressing need for ...

Males imprint their DNA by adding methyl modifications to it in a way that alters the activity of genes in order to promote ...

Selecting the right DNA methylation sequencing assay is vital to generating robust and reproducible data on epigenetic modifications. ©iStock, undefined D NA methylation is a widely studied epigenetic ...

Epigenetics, the mechanisms that control gene expression via modifications made to DNA, operate through two key approaches in eukaryotes. The first, histone modification, involves the modification of ...

These DNA methylation modifications can be stable throughout the life of the affected individual and may even be passed on to their children. This is of particular interest in epigenetics, which ...

Researchers have developed the first comprehensive atlas of allele-specific DNA methylation across 39 human cell types, revealing a complex landscape of epigenetic regulation. The study identified ...

A new review from Genes and Diseases sheds light on the pivotal role of LINE-1 elements in preimplantation development and totipotency, revealing their essential contributions to early mammalian ...

Background Epigenetics is the study of processes—beyond DNA sequence alteration—producing heritable characteristics. For example, DNA methylation modifies gene expression without altering the ...

Life X DNA™ builds on this model by analysing more than 25 methylation-specific genes and an additional 300 genes that may play a role in related biological processes. The methodology combines ...