Ferroptosis, a form of programmed cell death mediated by iron, has been a focus for its potential in cancer therapies. Now, researchers have discovered that lysosomal lipid peroxidation plays a ...

Scientists have discovered how iron in lysosomes can induce ferroptosis, offering a new route to target treatment-resistant ...

The team discovered that peroxidation of lysosomes plays a key role in the execution of ferroptosis-mediated cell death. Additionally, they found that lysosomal lipid peroxidation causes the ...

A new class of molecules capable of killing the cancer cells that are refractory to standard treatments and responsible for recurrence has just been developed. This crucial advance in the fight ...

For neurodegenerative diseases such as Alzheimer's and Parkinson's, treatment options are scant. New research by Stanford ...

Using this tool, they established that after autophagosomes form, they fuse to the lysosomal membrane ... and what parts of the cell can be eaten without causing cell death? Scientists ...

The team discovered that peroxidation of lysosomes plays a key role in the execution of ferroptosis-mediated cell death. Additionally, they found that lysosomal lipid peroxidation causes the membrane ...

Ferroptosis diagram. Iron is internalized in the cell via the protein CD44 present on its surface, allowing it to acquire metastatic properties and tolerance to standard treatments through epigenetic ...