He pointed out that only one liver has been transplanted “which precludes drawing generalisable conclusions or establishing robust patterns of clinical and immunological response” “Although ...

The cost is high, in part, because 90% of drugs do not pass animal and human clinical trials, so researchers must go back to the proverbial drawing ... of normal human liver biology because ...

Therefore, providing better in vitro models for interrogating human liver biology will have a major impact in the fields of toxicology and hepatology. In this report, we demonstrate that 3D bioprinted ...

There are other differences in liver biology as well. But if the researchers can make it work, extending preservation time could have profound effects on the transplant system. Livers could be ...

Orthotopic liver transplantation in the mouse is a powerful research tool that has led to important mechanistic insights into the regulation of hepatic injury, liver immunopathology, and ...

Back in May 2021, Swiss researchers removed the damaged liver of an organ donor, placed it in a novel machine that mimicked the human body's biology and treated it in that machine for three days.

Over 870 qualified scientists and physicians have pursued research careers in liver biology, disease and treatment because they received these grants early in their careers. "We received an ...

The research community has long needed a better model for studying human liver biology and disease, because there are outstanding hepatocyte diversity and associated functional orchestrations in ...