Similar changes likely affect kidney cell gene expression, potentially modifying protein production essential for normal filtration and transport functions. Nephron loss acceleration represents ...

It also focuses on the macula densa (MD) cells, located at the vascular pole of each nephron. Nephrons are ... help maintain ...

The 12th workshop will be held from May 12 - 16, 2025 focusing on hands-on whole kidney and single nephron function analysis and models of acute and chronic kidney disease. Please contact Dr. Volker ...

Each human kidney has about 1 to 2 million filtering units called nephrons that help purify our blood and remove waste ...

Using a mouse model of AKI, the research team first demonstrated the therapeutic potential of human iPS cell-derived nephron progenitor ... the deterioration of kidney function.

In preclinical studies, this combination of cells was able to induce new nephron formation, reduce disease and stabilize or improve multiple kidney functions, demonstrating long-term improvement ...