They do so because when an RTK becomes activated, the result is phosphorylation of specific tyrosines on the cytoplasmic tail, the intracellular portion of the receptor. This phosphorylation leads ...
2007.08.001. Madshus, I. H. & Stang, E. Internalization and intracellular sorting of the EGF receptor: A model for understanding the mechanisms of receptor trafficking. Journal of Cell Science 122 ...
Engineered cell therapies rely on synthetic receptors to transduce external signals into intracellular responses. The precise ...
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