We aimed to investigate whether the reduced incretin effect observed in patients with type 2 diabetes is a primary event in the pathogenesis of type 2 diabetes or a consequence of the diabetic state.

JMU scientists studied insulin-producing cells in fruit flies, finding that secretion is influenced by gut hormones, ...

"In humans, this phenomenon is known as the incretin effect," explains Dr. Ache. It suggests that insulin secretion is not ...

How does the body regulate the activity of insulin-producing cells in order to react quickly to changing conditions? Researchers have investigated this question.

Research has shed light on the intricate mechanisms of insulin production in fruit flies, revealing surprising parallels with ...

1 In this article, we explore the impact of incretin-mimetic drugs on muscle health and what can be done to limit these severe side effects. Incretins are intestinal hormones secreted in response to ...

Eli Lilly has invested heavily into obesity, dominating the landscape—alongside semaglutide maker Novo Nordisk—with its ...

reducing food intake and having trophic effects on the pancreatic islet cells. [9] These incretin hormones have been implicated recently in the pathogenesis of Type 2 diabetes. GLP-1 is ...

Cardiorenal effects of SGLT2 and incretin agents SGLT2 inhibitors work directly on the kidney through the SGLT2 cotransporter to directly improve energy metabolism and function in the kidney.

Terence Flynn, Morgan Stanley, inquired about Zepbound payer dynamics and access. Patrik Jonsson explained that Medicare coverage related to obstructive sleep apnea (OSA) is anticipated in the second ...

Common side effects were mild-to-moderate gastrointestinal issues, aligning with other incretin-based therapies. Get real-time earnings alerts before the market moves and access expert analysis ...