In whole-genome assembly, the BAC fragments (red line segments) and the reads from five individuals (black line segments) are combined to produce a contig and a consensus sequence (green line).

A research team has achieved a gapless assembly of Syntrichia caninervis's genome, totaling 323.44 Mbp with an N50 value of 24.41 Mbp and a single-base accuracy exceeding 99.999%, making it the ...

Alternatively, reads can also be aligned to a reference genome to identify small genetic variations (below right). Where de novo assembly can be thought of as assembling a puzzle without the use of ...

Many colloquially refer to this effort as “sequencing the human genome.” However, this process actually involves two steps: the sequencing of DNA, in which a specialized machine reads the sequences of ...

Surbhi Grewal, assistant professor, School of Biosciences, led the wild wheat variety study at the University of Nottingham. NOTTINGHAM, ENGLAND — Scientists have mapped the genome sequence for a wild ...

Scientists have successfully mapped the genome sequence of Aegilops mutica, a wild relative of wheat, shedding light on its genetic diversity and ...

In the last few decades, the evolution of sequencing technologies has revolutionized genome analysis, pushing towards the design of scalable computational approaches for the analysis of massive ...