In a groundbreaking review titled "The Mechanism of Ferroptosis and its Related Diseases," Feng and his colleagues from the Department of Urology and the Institute of Urology, State Key Laboratory ...

Zooming in and out of ferroptosis in human disease. Higher Education Press . Journal Frontiers of Medicine DOI 10.1007/s11684-023-0992-z ...

It underscores the role of ferroptosis in the pathogenesis of various diseases, including cancers, neurodegenerative disorders, cardiovascular diseases, and more.

Research Progress on Ferroptosis Mechanism in Endometrial Cancer. Journal of Biosciences and Medicines, 13, 65-74. doi: 10.4236/jbm.2025.137005 . Endometrial Cancer (EC) is an epithelial malignant ...

A team of researchers at Tohoku University has unearthed some of the biological mechanisms of ferroptosis, a recently discovered type of regulated cell death that is triggered by iron and the ...

Heterogeneous Hippo pathway (YAP/TAZ) activation in lung adenocarcinoma drives tumor progression by enabling ferroptosis ...

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression. Ferroptosis, driven by excessive lipid peroxides and iron-dependent reactive ...

More specifically, the team identified two key mechanisms for 25-OHC-induced ferroptosis. ... This result has significant implications for understanding how diseases like ALS might progress, ...

In addition, ferroptosis markers strongly correlate with lung injury severity in a COVID-19 lung disease model using male Syrian hamsters.” Ferroptosis was first reported by Stockwell in 2012.

They will “serve as the stepping stone for the development of novel therapeutic strategies for diseases where ferroptosis has been implicated,” Conrad said in a statement.

While suppressing ferroptosis has been tabled as a target for Alzheimer’s before, these new insights have huge potential for new therapeutics to slow the progression of neurodegenerative diseases.