New electron microscopy technique limits membrane destruction. ... A 3D model of the endoplasmic reticulum ... is a critical regulator of whether cells under stress live or die. Her goal for ...

SLC35B1 transports ATP into the ER, and its structure offers potential for targeted therapies in diseases linked to ER stress. A team of scientists has solved a long-standing question in cell biology ...

Scientists at Forschungszentrum Jülich have now been able to gain fascinating new insights using cryo-electron microscopy. Their work is published in the journal Nature Structural & Molecular ...

Endoplasmic reticulum stress or malfunction can contribute to neurodegenerative diseases like Alzheimer’s ... people have had to use electron microscopes to look at the ER,” says Mark ...

A team of scientists has answered a long-standing question in cell biology, uncovering how the cell’s main energy currency, ATP, is transported into the endoplasmic reticulum (ER). Disrupted energy ...

Using cryo-electron microscopy, ... Our study reveals a molecular mechanism by which mechanical stress can be converted to biochemical signaling via protein-lipid interactions in unprecedented ...

Researchers have created an electron microscopy ... stress live or die. Her goal for developing this technique was to be able to see where HYPE goes once it enters the endoplasmic reticulum, ...