Biliary Tract Infection in Patients with Acute Biliary Pancreatitis . Boudewijn De Waele, Yves Van Nieuwenhove, Sabine Lauwers, Georges Delvaux. Disclosures. In This Article.

Biliary tract infections (BTI), often linked to structural abnormalities like bile duct stones, pose significant treatment challenges due to drug-resistant bacteria like Pseudomonas aeruginosa.

Compared with other maternal infections, intestinal infection and genitourinary tract infection increased the risk for biliary atresia. Antepartum viral enterocolitis also increased risk.

Acute cholangitis is a severe, bacterial infection of the biliary tract precipitated by an obstruction that often results in systemic inflammation and, in some cases, life‐threatening sepsis.

Serious AEs occurred in 53% of patients and included biliary obstruction (15%), biliary tract infection and sepsis (each in 8%), pneumonia (5%), diarrhea and gastric obstruction ...

Medically reviewed by Jay N. Yepuri, MD Primary biliary cholangitis (PBC), also known as primary biliary cirrhosis, is a chronic and progressive disease that damages and can eventually destroy the ...

Tovecimig (CTX-009) meets primary endpoint in the ongoing randomized phase 2/3 study in patients with biliary tract cancer. News release. Compass Therapeutics. April 1, 2025.

Tovecimig combined with paclitaxel showed a 17.1% response rate in biliary tract cancer, outperforming paclitaxel alone. The COMPANION-002 study reported lower progressive disease rates with tovecimig ...

"Biliary tract cancer is comparatively rare, but it's aggressive and spreads fast. Our accrual of more than 450 patients in a little more than two years really shows there is a need for new ways ...

References: Jazz Pharmaceuticals announces US FDA approval of Ziihera ® (zanidatamab-hrii) for the treatment of adults with previously treated, unresectable or metastatic HER2-positive (IHC 3 ...

On November 20, 2024, the U.S. Food and Drug Administration granted accelerated approval to the drug zanidatamab (Ziihera ®) to treat advanced and metastatic bile duct cancer (cholangiocarcinoma) and ...