Pattern on the Antinuclear Antibody-HEp-2 Test Is a Critical Parameter for Discriminating Antinuclear Antibody-Positive Healthy Individuals and Patients With Autoimmune Rheumatic Diseases Study ...

Antibodies that attack healthy proteins within the cell nucleus are called antinuclear antibodies ... as both a ratio (called a titer) and a pattern, such as smooth or speckled.

diffuse and peripheral patterns. It therefore seems likely that several nuclear antigens are capable of stimulating production of antibody of all 3 immunoglobulin classes. Antinuclear factor was ...

The presence of antinuclear antibodies (ANA) indicates the possibility ... and considered positive if a well defined IIF pattern was identified. "The ANA-HEp-2 test is positive in a sizable ...

Antinuclear antibodies (ANA) are autoantibodies directed ... as well as the staining pattern, which reflects the way the antibody binds to the nucleus. This shows which antigens are being bound ...

The most frequent ANA patterns in PBC sera are the 'speckled ... significance in PBC patients. † Correlation of antinuclear antibodies with unfavorable disease course.

The immunoglobulin class and patterns of antinuclear-antibody staining were similar to those associated with systemic lupus erythematosus. Four of 15 patients without clinical hydralazine toxicity ...

Antinuclear antibodies are a unique group of autoantibodies ... The results—positive or negative, titer, pattern, and subset test results—can provide healthcare providers with valuable clues ...

What Is an Antinuclear Antibody Test? An antinuclear antibody test is a blood test that looks for certain kinds of antibodies in your body. It’s also called an ANA or FANA (fluorescent ...