A new study reports that mirodenafil, a newly developed oral phosphodiesterase type 5 (PDE5) inhibitor, is an efficacious and safe treatment for erectile dysfunction (ED). Many men with ED ...

The introduction of inhibitors of the cyclic GMP phosphodiesterase (PDE) 5 into clinical urology is mainly the result of the characterization of the physiology of nonvascular and vascular penile ...

tablet the first phosphodiesterase 5 (PDE-5) inhibitor in the US to undergo an AUT. AUTs are critical in assessing the real-world application of medicines, ensuring that consumers can self ...

The two products are some of the first clinically tested nasally-administered PDE-5 inhibitors, sildenafil (Viagra) and vardenafil (Levitra). The company announced the products after in-vivo ...

and a phosphodiesterase-5 (PDE-5) inhibitor. In March, just days prior to sotatercept's approval, macitentan/tadalafil become ...

Data Synthesis: Cilomilast is a second-generation PDE4 inhibitor with antiinflammatory ... cilomilast improved ~3.6 points vs placebo worsened ~0.5 points (p < 0.001) pts. exacerbation-free ...

Objective: Given the therapeutic and non-therapeutic use of the tadalafil, (phosphodiesterase-5 inhibitor, PDE-5i), we examined its effects on anaerobic performance indices. Methods: In total, 12 well ...