Using this technique, researchers could more easily study how the 3D organization of the ... of cells to calculate an average structure for a section of chromatin, or on single cells to determine ...

“We are finding the 3D structure of the genome,” said Satoshi ... “CTCF-mediated 3D chromatin sets up the gene expression program in the male germline.” “This is really showing us ...

Research shows UV radiation modifies 3D genome structure, affecting DNA damage response and gene activity, offering insights ...

"We are finding the 3D structure of the genome," said Satoshi ... More information: Yuka Kitamura et al, CTCF-mediated 3D chromatin sets up the gene expression program in the male germline ...

The proper folding of the chromatin structure plays a crucial role in the regulation of genomic DNA functions, its disruption leading to various diseases. Therefore, understanding the chromatin ...

Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

“We are finding the 3D structure of the genome,” said Satoshi Namekawa, professor of microbiology and molecular genetics at the University of California, Davis and senior author on one of the ...